How should an assessment for suspected Dementia be performed?

Your Expert Guide to Early, Accurate Diagnosis and Personalised Care

At our leading private memory clinic in London, we understand the profound anxiety that memory concerns can bring—for individuals and families alike. Questions about dementia—and particularly Alzheimer’s disease—often arise when changes in memory, thinking, or daily function become noticeable. These changes can feel unsettling, even frightening, and the journey toward clarity and answers is rarely straightforward.

At our Harley Street memory clinic, we are dedicated to providing a meticulous, compassionate, and state-of-the-art diagnostic pathway. Our mission is to ensure that every person receives not only an accurate diagnosis but also a clear, actionable plan for the future. And now, with the arrival of the LucentAD® Complete Alzheimer’s Blood Test, the landscape of dementia diagnosis is being transformed—offering hope through earlier and more precise detection than ever before.


What Does Dementia Really Mean?

The term dementia refers not to one single condition, but to a group of symptoms characterised by significant impairment in memory, reasoning, language, and other thinking abilities—severe enough to interfere with everyday life. The most common cause of dementia is Alzheimer’s disease, but other important causes include vascular dementia, frontotemporal dementia, and Lewy body dementia.

Each of these conditions affects the brain in unique ways, which is why an accurate, detailed assessment is essential. A rushed or incomplete evaluation can lead to incorrect labelling—resulting in missed opportunities for tailored treatment, management, and support.

At our clinic, we believe that getting the diagnosis right matters deeply—because behind every diagnosis is a person, a family, and a future that deserves clarity and care.


The Gold Standard in Dementia Assessment: A Step-by-Step Approach

We pride ourselves on offering one of the most comprehensive dementia assessments in London. Each assessment is meticulously designed to uncover not just whether dementia is present, but what type it is—and how best to manage it.

1. Holistic Clinical History

A detailed history is the cornerstone of any accurate dementia diagnosis. We take time to listen—both to the individual and to a close family member or friend. This collateral history helps us understand:

  • Changes in memory
  • Difficulties with language or communication
  • Challenges in executive function (planning, judgement)
  • Alterations in visuospatial awareness

We explore the story behind the symptoms—because no two individuals are the same.

2. Physical Examination

Subtle neurological signs, including Parkinsonian features or balance issues, can point towards specific types of dementia such as Lewy body dementia or Parkinson’s-related cognitive decline. A physical exam is essential for a complete picture.

3. Cognitive Testing

Specialist paper-based assessments help quantify the degree and pattern of cognitive changes. Tools such as the ACE-IIIor MoCA allow us to map out the strengths and weaknesses of memory, attention, language, and problem-solving.

4. Laboratory Investigations

A comprehensive cognitive blood panel is performed to rule out reversible causes of memory problems, such as:

  • Vitamin B12 deficiency
  • Thyroid dysfunction
  • Infections
  • Metabolic imbalances

These conditions are often overlooked but may mimic or exacerbate cognitive symptoms.

5. Advanced Brain Imaging

State-of-the-art MRI brain scans are vital in identifying:

  • Early signs of neurodegeneration (brain cell loss and shrinkage)
  • Evidence of vascular damage (small strokes, blood vessel disease)
  • Structural changes consistent with different types of dementia

In some cases, when MRI results are inconclusive, we recommend cutting-edge functional brain imaging:

  • FDG-PET scans to detect early metabolic brain changes
  • Amyloid PET scans to identify Alzheimer’s hallmark plaques
  • DAT scans to assess for dopamine-related disorders

A Revolution in Early Detection: The LucentAD® Complete Alzheimer’s Blood Test

We are proud to be among the first in the UK to offer the LucentAD® Complete, an innovative Alzheimer’s blood test that is reshaping how we detect and diagnose early cognitive decline.

This multi-analyte blood test detects biomarkers associated with Alzheimer’s disease, potentially years before traditional imaging can reveal changes. By identifying disease at the molecular level, the LucentAD® test allows for:

  • Earlier intervention
  • Access to lifestyle and therapeutic strategies that can slow progression
  • Empowerment through knowledge and future planning

The LucentAD® Complete is available as part of our same-day dementia assessment service at our private Harley Street clinic—bringing next-generation diagnostics to those who need answers without delay.


Life Beyond the Diagnosis: Personalised Dementia Care

A diagnosis is never the end of the story. At our private memory clinic, we are committed to supporting individuals and families every step of the way with:

  • Evidence-based brain health strategies
  • Consideration of cognitive-enhancing medications where appropriate
  • Access to allied healthcare professionals including clinical psychologists, dietitians, physiotherapists, and occupational therapists

Our goal is to optimise quality of life, preserve independence, and provide emotional and practical support—not just to the person diagnosed, but to their family and loved ones as well.


Why Choose Our Private Dementia Assessment on Harley Street?

Choosing us means choosing:

  • Immediate access to specialists with deep expertise in cognitive neurology
  • Compassionate, unhurried consultations
  • The latest diagnostics including the LucentAD® Alzheimer’s Blood Test
  • Same-day answers where possible, with robust, evidence-led management plans

Whether you are concerned about memory loss in yourself or seeking a private dementia diagnosis for a parent, we are here to guide you towards clarity and peace of mind.


Take the First Step Toward Clarity and Care

If you or someone you care about is showing signs of memory difficulties, don’t wait. Early diagnosis leads to better outcomes and empowers informed decision-making.

📞 Call us today to book your private cognitive assessment in London